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Post Orgasmic Illness Syndrome (POIS) – Twice Shy About Coming

Like fireworks without the bang, post-orgasmic illness syndrome (POIS) leaves guys gun shy about ejaculating. Rare, but it packs a punch in your sex life.

Sean Christopher
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Like fireworks without the bang, post-orgasmic illness syndrome (POIS) leaves guys gun shy about ejaculating. Rare, but it packs a punch in your sex life. No one knows how common of a sexual malady POIS is, but most recent research involving a Dutch research physician and forty-five post-orgasm illness syndrome sufferers suspects afflicted men of semen allergy. Marcel Waldinger, a professor of sexual psychopharmacology at Utrecht University in the Netherlands, published the two studies in the Journal of Sexual Medicine.

What Is POIS?

Documented in 2002, POIS still remains relatively unknown among doctors and most scholarly writing. When I asked my own doc, he reached for the bookshelf, turned up nothing, and said, huh. Still, to sufferers, post-orgasm illness syndrome is very real, very physiological, and most debilitating.

POIS seems to be more connected with an ejaculation of semen than with an orgasm. For some guys, symptoms appear mere moments after ejaculation, while for others twenty-four hours or more pass before noticing the effects.

Guy symptoms for POIS can include mental symptoms, physical symptoms or both and can last anywhere from a few hours to several days:

  • Depression
  • Mental fatigue and inability to concentrate
  • Fogginess
  • Anxiety
  • Headache
  • Flu-like symptoms including sore throat
  • Diarrhea
  • Muscle ache
  • Fatigue

The threat of post-ejaculatory depression no doubt hangs a foreboding flag of fear over a guy’s sex bed or masturbatory moments. A slamming headache, flu-like symptoms, or a couple of days of anxiety definitely provokes a guy to think twice before coming again.

POIS can create tension and mistrust in an otherwise sexual relationship because of men’s reluctance to talk with their partners about their symptoms. Few men seek medical help for these same reasons or because they don’t make the connection between their symptoms and the ejaculation they enjoyed a few hours earlier.

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What can be done? Dr. Marcel Waldinger suggests allergen immunotherapy, a long-term treatment. This is most likely years off, however. Men have experimented with dozens of remedies rewarding them with varying results from nutmeg to fenugreek, certain hormone therapies including testosterone as well as supplements like 5-HTP and omega-3 from fish oil, my personal favorite.

Other methods guys use to cope with post-orgasmic illness syndrome can include everything from avoiding sexual activity altogether to planning their ejaculations in order that symptoms don’t interfere with important things like work and social events. Some men can ward off some or all symptoms by masturbating to non-ejaculatory orgasm soon after ejaculation. Others cultivate a sexual lifestyle involving only occasional ejaculation. A few men report avoiding POIS altogether with a subsequent ejaculation immediately after the offending first.

Fortunately, research continues and the online community of post-orgasmic illness syndrome support is growing and organizing as the syndrome becomes better known and men recognize the characteristics of their own and others’ symptoms. Information, a supportive community with others, and openness with sexual partners and friends are as important as any remedy.

Leave a comment at the bottom of the page with your own POIS experiences or even suspicions. You and OG can add a piece to relieving some of the burdens of post-orgasm illness syndrome. Thanks for chipping in!

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  1. Removal of the testicals will fix this problem. if you want to have children still ytou can choose to freeze your sperm

    1. Thanks, info girl. I’m thinking removing the testicles might be an extreme case. Most guys are pretty fond of “the boys”.

  2. Thank you for the presentation of our health problem. It was not possible to speak of this thing, even in recent years. Most physicians and scientists refused that there are negative things about sex. It was a long fight to change minds on this subject.

  3. Thanks for spreading awareness. I like the way you talked about POIS since a lot of other people talk as if it’s a joke. I especially liked when you said “Still, to sufferers, post orgasm illness syndrome is very real, very physiological, and most debilitating.”

    It’s true and it’s very debilitating not like the normal tiredness after sex a lot of normal guys seem to get. This disease will ruin your life if you get a bad enough form of it. I barely have energy these days to get up and leave my bed to go to the bathroom or to eat.

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